Day 2 :
Keynote Forum
Yibin Feng
The University of Hong Kong, Hong Kong
Keynote: Drug discovery from chinese medicines: Update and prospect
Time : 12.00-12.20
Biography:
Yibin Feng is currently an Associate Professor cum Associate Director (Education) in School of Chinese Medicine, the University of Hong Kong. Dr. Feng awarded Bachelor degree in Chinese Medicine from Mainland China. He awarded his PhD degree in molecular medicine from Hokkaido University School of Medicine and finished postdoctoral research in the same University in Japan. Dr. Feng’s research interest focuses on clinical trial and experimental study for cancer, diabetes, hepatic and renal diseases by using recently developed techniques. He has published over 200 publications in these areas and serve as editor and reviewer for over 50 international journals.
Abstract:
Traditional Chinese Medicine (TCM) has been used in China over two thousand years. Chinese medicines are medication materials including Chinese medicinal plants, animal parts and menerals. Chinese medicines have been intensive stuided for their scientific basis and evidence-based medicine. In the past years, several drugs and drug candidates were discovered from Chinese Medicines. Chinese medicines prefre use mutiple materials mix together to single materials to treat diseases. As a drug discovery resource and complementary and alternative medicine, Chinese Medicines no matter single pure compound or mutitple components are drug candidates. This topic will review drug discovery from Chinese medicines in the past, present and draw conclusion in terms of chmistry, pharmacology and clinical medicine. To discover more drug candidates, research model and platform for Chinese medicines are required somthing new in the fuuture. This work was financially supported in part by grants from RGC General Research Fund, Hong Kong SAR (Project Code: 10500362), Gala family trust for natural products (Project code: 200007008) and Goverment-Matching Funding (Project code: 207060411).
Keynote Forum
Yue Wei Guo
Shanghai Institute of Materia Medica- Chinese Academy of Sciences, China
Keynote: Exploring for bioactive secondary metabolites from the Chinese medicinal mangroves
Time : 12.20-12.50
Biography:
Yue Wei Guo has completed his PhD from Naples University and Post-doctoral studies from Istituto di Chimica Biomolecolare-CNR, Italy and Hokkaido University, Japan. He is the Professor of SIMM-CAS, a premier drug R/D organization. He has published more than 350 papers in reputed journals and has been serving as an Editorial Board Member of repute.He is intersted in Ethnobotany.
Abstract:
Mangroves comprise a large number of various salt-tolerant plants growing in tropical and subtropical intertidal estuarine zones. Historically, many mangrove plants were used to treat various diseases in Traditional Chinese medicine. Currently, the secondary metabolites found in mangroves represent an extremely rich source of novel chemical diversity for academic drug discovery and chemical biology programs. It is particularly true that the mangroves from Southern Coast of China are very prolific producers of bioactive natural products. Our group at SIMM has long been engaged in searching for novel secondary metabolites with pharmacological potential from Chinese mangrove medicinal plants. In collaboration with biologists and pharmacologists at SIMM, many mangroves used as fork medicine were chemically investigated and numerous novel isolates obtained were pharmacologically screened for activity in a variety of cell-based and pure enzyme assays designed to identify promising lead compounds for the development of drugs in the therapy of human diseases. This presentation will discuss examples of bioactive metabolites (structures and activities) from our recent discovery efforts.
- Track 10: Nutraceuticals