Anamika Mubayi
University of Allahabad, India
Title: Green mediated nanoparticles with improved antimicrobial efficacy
Biography
Biography: Anamika Mubayi
Abstract
The interdisciplinary scientific rationalization of traditional drugs is of great significance to present civilizations as it has a big role in supporting basic health care needs. Mainly related to treatments associated with aging, prolonged communicable diseases, traditional drugs offer promising alternatives to modern medicines. The latest trend in ethnopharmacology have led to the undiscerning use of chemical products which has given rise to several problems comprising environmental pollution, harmful residues, chemical drugs and resistance against microbes. This has strived exploration into alternate methods. The outcome from the current analysis will definitely give momentum to the area of medicinal plant research to develop viable, efficient and nontoxic substitutes against usual antimicrobial compounds. In this paper, the nanoparticles were synthesized from Moringa oleifera and their antimicrobial activity was assessed. Antimicrobial potential of leaves has been assessed for both the extracts, with and without AgNP, on different strains viz. Staphylococcus aureus, Klebsiella pneumoniae, Escherichia coli, Pseudomonas aeruginosa and Enterococcus faecalis. Extent of inhibitory effect of both the extracts was assessed by minimum inhibitory concentration method over a concentration range of 0.075-2.4 mg/ml and standard zone of inhibition (ZOI) assay. The nanoparticles showed ZOI against almost all the studied bacteria. The water extract was found to have an antibacterial activity against gram positive and gram-negative strains. The bactericidal effect of nanoparticles is due to their size which helps them to interact with microorganisms and therefore these green nanoparticles help in increasing the antibacterial potential of plants.